Ethyl 6-bromonicotinate

Ethyl 6-bromonicotinate - Names and Identifiers

Name	Ethyl 6-bromonicotinate
Synonyms	Ethyl 6-bromonicotinate Ethyl 6-broMonicotinate 6-Bromonicotinicacidethylester 6-Bromonicotinic acid ethyl ester ethyl 6-bromopyridine-3-carboxylate ETHYL 6-BROMOPYRIDINE-3-CARBOXYLATE Ethyl 2-bromopyridine-5-carboxylate Ethyl 2-BroMo-5-pyridinecarboxylate Ethyl 2-bromo-5-pyridinecarboxylate 6-BROMOPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 6-Bromopyridine-3-carboxylic acid ethyl ester 6-BroMo-3-pyridinecarboxylic Acid Ethyl Ester 3-Pyridinecarboxylic acid, 6-broMo-, ethyl ester
CAS	132334-98-6

Ethyl 6-bromonicotinate - Physico-chemical Properties

Molecular Formula	C8H8BrNO2
Molar Mass	230.06
Density	1.501
Boling Point	292℃
Flash Point	131℃
pKa	-1.14±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

Ethyl 6-bromonicotinate - Introduction

Ethyl 6-bromonicotinate, also known as 6-bromo-2-nicotinoyl acetate, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Ethyl 6-bromonicotinate is a colorless or slightly yellow solid.
-Solubility: Soluble in common organic solvents, such as ethanol, ether and chloroform.
-Melting point: Depending on the experimental conditions, the melting point range is usually between 40-50 degrees Celsius.

Use:
-Pharmaceutical field: Ethyl 6-bromonicotinate is an important intermediate and raw material. It plays a key role in the synthesis of drugs and bioactive molecules.
-Pesticide field: Due to its special structure, 6-bromo-nicotinic acid ethyl ester also has certain application prospects in pesticide chemistry.

Preparation Method:
The preparation of ethyl 6-bromonicotinate can be carried out by one of the following methods:
-Add bromine to the reaction mixture of ethyl nicotinate, and achieve the synthesis of the desired product through appropriate reaction conditions, such as controlling temperature and reaction time.
-Bromination of ethyl nicotinate under alkaline conditions to form ethyl 6-bromo nicotinate.

Safety Information:
-The compound may have certain toxic and irritating effects on the human body, so it needs to be used carefully and pay attention to protective measures.
-When using ethyl 6-bromonicotinate, follow laboratory and safety practices, and wear appropriate protective equipment, such as gloves and goggles.
-Avoid inhalation, ingestion or contact with skin and eyes. In the operation should pay attention to good ventilation conditions, and try to avoid the generation of dust and steam.
-When storing and handling ethyl 6-bromonicotinate, it should be stored in a sealed container, away from fire and oxidizing agents.

Last Update：2024-04-09 21:04:16